Meet the PI - Peng Fei

Meet the PI - Peng Fei

1. What is the research focus of your lab? 

Our lab primarily investigates morphogenesis during embryonic development. To be more specific, we are fascinated by the “shapes” formed in embryos, including body axes, organ shapes, and patterns. We also apply these developmental principles to embryonic stem cells to generate specific patterns and shapes, known as organoids and embryoids. 

2. How long have you been working with zebrafish? How long have you had your own lab? 

I was first introduced to zebrafish in 2005 during my PhD studies in Shanghai. My doctoral advisor was Dr. Zhu Chen, a renowned geneticist and hematologist. I studied (accidentally) left-right asymmetry under the guidance of Dr. Ting-Xi Liu, who was trained by Dr. Tomas Look at the Dana-Farber Cancer Institute. Subsequently, I joined Drs. Bernard and Christine Thisse’s laboratory at the University of Virginia to continue my research on early development. Their profound passion for science and rigorous approach to research have had a lasting influence on my scientific career. Later, I learned the principles of systems biology from Dr. Sean Megason at Harvard University, where I also met many like-minded friends who are now actively contributing to their respective research fields. In 2017, I returned to China and established my own laboratory at Zhejiang University in Hangzhou, continuing my investigation into morphogenesis during embryonic development. 

3. Where were you born/where did you grow up? 

I was born and raised in Zibo, Shandong. It’s in northern China and used to be a city known for its heavy industry centered around mining and petroleum. It is famous for its ceramics and colored glaze. In recent years, it gained nationwide attention for its unique barbecue style. 

4. Tell us something about yourself in one sentence. 

I enjoy making jokes, although they don’t always seem to land well. 

Science

5. Which of the current projects in your lab you are most excited about? 

I’m particularly excited about our comparative study of tail lengths between zebrafish and loach, as well as the investigation into the mechanical influences on EVL’s properties during epiboly. 

6. What advice would you give to someone considering a career in science/research? 

I firmly believe in this saying: Interest is the best teacher.

7. Which part of the PI job you enjoy the most? Why? 

I enjoy discussions with students and colleagues. I often find inspiration and clarity through these interactions, and hopefully, the same is true for them. 

Outside of work

8. What do you enjoy doing outside of work/lab? 

I’m an avid table tennis enthusiast. I used to sneak out to play during my time in Sean’s lab, and I still play regularly now. I also enjoy hiking and reading non-academic books. 

9. What career would you have liked if you were not a scientist? 

A teacher or a physician.